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Consensus Recommendations for the Clinical Application of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Depression

By Shawn M. McClintock, PhD, MSCS,  Irving M. Reti, MBBS, Linda L. Carpenter, MD, William M. McDonald, MD, Marc Dubin, MD, PhD, Stephan F. Taylor, MD, Ian A. Cook, MD, John O’Reardon, MD, Mustafa M. Husain, MD, Christopher Wall, MD, Andrew D. Krystal, MD, Shirlene M. Sampson, MD, Oscar Morales, MD, Brent G. Nelson, MD, Vassilios Latoussakis, MD, Mark S. George, MD, and Sarah H. Lisanby, MDb, on behalf of both the National Network of Depression Centers rTMS Task Group and the American Psychiatric Association Council on Research Task Force on Novel Biomarkers and Treatments.

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To provide expert recommendations for the safe and effective application of repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depressive disorder (MDD).

The consensus statement is based on a review of extensive literature from 2 databases (OvidSP MEDLINE and PsycINFO) searched from 1990 through 2016. The search terms included variants of major depressive disorder and transcranial magnetic stimulation. The results were limited to articles written in English that focused on adult populations. Of the approximately 1,500 retrieved studies, a total of 118 publications were included in the consensus statement and were supplemented with expert opinion to achieve consensus recommendations on key issues surrounding the administration of rTMS for MDD in clinical practice

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