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Treatment Resistant Depression: Case Report

Authors: Daniel Amarasinghe, BS, MSU-Wayne State University School of Medicine, Department of Psychiatry and Behavioral Neurosciences; Bassem Saad, MD-Wayne State University School of Medicine, Department of Psychiatry and Behavioral Neurosciences; Carly Brin, LMSW-Wayne State University School of Medicine, Department of Psychiatry and Behavioral Neurosciences; Nicholas Mischel, MD, PhD-Wayne State University School of Medicine, Department of Psychiatry and Behavioral Neurosciences

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Background: Treatment-resistant depression (TRD) is a relatively common occurrence in clinical practice, with up to 50% to 60% of patients not achieving adequate response following antidepressant treatment. Repetitive Transcranial Magnetic Stimulation (rTMS) treatment for Major Depressive Disorder MDD involves stimulation of the dorsolateral prefrontal cortex which plays an important role in cognitive function and mood. Specific cognitive symptoms can occur as part of MDD.

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