Category Archives: Research
Evaluation of repetitive transcranial magnetic stimulation for treatment-resistant major depression and the impact of anxiety symptoms on outcome
Objective: The aim of this study was to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) in patients with treatment-resistant major depression and to explore the relationship between the outcome and comorbid anxiety symptoms.
High-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Improves Functional Recovery by Enhancing Neurogenesis and Activating BDNF/TrkB Signaling in Ischemic Rats
Repetitive transcranial magnetic stimulation (rTMS) has rapidly become an attractive therapeutic approach for stroke. However, the mechanisms underlying this remain elusive. This study aimed to investigate whether high-frequency rTMS improves functional recovery mediated by enhanced neurogenesis and activation of brain-derived neurotrophic factor (BDNF)/tropomyosin-related kinase B (TrkB) pathway and to compare the effect of conventional 20 Hz rTMS and intermittent theta burst stimulation (iTBS) on ischemic rats. Rats after rTMS were sacrificed seven and 14 days after middle cerebral artery occlusion (MCAO), following evaluation of neurological function.
Transcranial DC Stimulation: Ready for Regular Use in Treating Major Depression?
Studies of transcranial direct-current stimulation (tDCS), which is one of several emerging biological nonpharmacologic interventions proposed to treat depression, have had mixed results. Now a team of investigators[1] from the University of São Paulo, Brazil, have undertaken a systematic review and meta-analysis of individual patient data to assess tDCS efficacy and explore individual response predictors.
The impact of cerebellar transcranial direct current stimulation (tDCS)
The cerebellum has been shown to be important for skill learning, including the learning of motor sequences. We investigated whether cerebellar transcranial direct current stimulation (tDCS) would enhance learning of fine motor sequences. Because the ability to generalize or transfer to novel task variations or circumstances is a crucial goal of real world training, we also examined the effect of tDCS on performance of novel sequences after training.
Transcranial Magnetic Stimulation Modulates Resting EEG Functional Connectivity Between the Left Dorsolateral Prefrontal Cortex and Limbic Regions in Medicated Patients With Treatment-Resistant Depression
High-frequency left prefrontal repetitive transcranial magnetic stimulation (rTMS) has been shown to have efficacy in treatment-resistant depression. However, the effects of rTMS on functional connectivity are still not clear.
Did You Know There Are 4 Different Types of Depression?
Depression therapies range from lifestyle methods such as talk therapy and exercise, medicinal treatments such as prescription antidepressants, medical treatments such as transcranial magnetic stimulation or, in particularly tough cases, electroshock therapy. Up until now, deciding which therapies would work best for which patient has been a matter of trial and error, but this new Cornell research will help doctors match the type of depression someone has to the best treatment for that version specifically.
Stimulating the brain can bring back forgotten short-term memories
Some hopeful news for those who can’t remember new people’s names: stimulating the brain with a magnetic pulse can bring back forgotten short-term memories, as long as we know that we’ll need that information later.
Brain stimulation guides people through an invisible maze
You’re stuck in a maze. You can’t see the walls, or the floor. All you have to navigate is a device on your head stimulating your brain to tell you which way to go. In an experiment at the University of Washington in Seattle, participants solved a maze puzzle guided only by transcranial magnetic stimulation (TMS). The findings suggest that this type of brain prompt could be used to augment virtual reality experiences or help give people who are blind “visual” information about their surroundings.